These wipes are gentle enough for everyday use. Use exactly as directed on the label, or as prescribed by your doctor. Preparation H Soothing Relief Cooling Spray is an innovative new way to treat butt discomfort, offering targeted relief from burning and itching associated with hemorrhoids. Ask a doctor or pharmacist before using over-the-counter medicines that may contain ingredients similar to phenylephrine rectal. Hemorrhoids are most common among adults ages 45 to 65. Who should not take Preparation H Ointment With Applicator? PREPARATION H products can be found near the pharmacy or digestive health aisle at most retail, grocery, mass and drugstore outlets. Learn more about hemorrhoids. This is not a complete list of possible side effects. PREPARATION H Hemorrhoid Symptom Treatment Suppositories, Burning, Itching and Discomfort Relief (48 Count) 4.6 out of 5 stars. For example, fever-reducing medications such as acetaminophen may be administered rectally if you cannot take the oral versions due to vomiting or other issues that might otherwise prevent you from swallowing liquids or tablets. This medication is used to temporarily relieve swelling, burning, pain, and itching caused by hemorrhoids. We do not recommend the use of PREPARATION Hfor any condition other than the uses indicated on the label. Wash your hands and cleanse the affected area by patting or blotting with an appropriate Advances in rectal drug delivery systems. Remain lying down. UNC Eshelman School of Pharmacy: "Preparation of Suppositories.". External Hemorrhoids, How to Insert a PREPARATION H Suppository, How to Apply PREPARATION H Ointment, Gels and Creams, How to Apply PREPARATION H Multi-Symptom Pain Relief Cream, How to Apply PREPARATION H Ointment with an Applicator, PREPARATION HRapid Relief with Lidocaine Cream, https://www.chpa.org/Monograph_FSA_CARES.aspx. During pregnancy, this medication should be used only when clearly needed. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Yes! Read more about treating flare-ups. Properly discard this product when it is expired or no longer needed. This is not a complete list of possible side effects. Yes. Easily get to the bottom of your hemorrhoid symptoms without the mess. For one, a pregnant woman's enlarged womb increases pressure in the hemorrhoid veins. Ns usamos cookies e outras tecnologias semelhantes para melhorar a sua experincia, personalizar publicidade e recomendar contedo. The Difference Between Internal vs. With proper care and lifestyle changes, you can get relief from hemorrhoid flare-ups and help reduce the risk of them reoccurring. The content of this site is intended for US audiences only. Phenylephrine rectal may also be used for purposes not listed in this medication guide. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Do not double the dose to catch up. See what sizes your favorite PREPARATION Hproducts come in. Flush only one wipe at a time. The best part is, they did it without drugs, over the counters and without risky Gamma Knife surgery is an effective treatment option for people with certain brain tumors, lesions, or other conditions that originate in the brain. This medication does not usually have bothersome side effects when used as directed. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you notice other effects not listed above, contact your doctor or pharmacist. The suppository is about the size of a grain of rice. This is not a complete list of possible side effects. Lie on your left side with the right knee bent. You can use latex gloves or finger cots to protect your fingers while inserting the suppository. We avoid using tertiary references. Suppositories have a base made from substances like gelatin or cocoa butter that surrounds the drug. https://www.drugs.com/sfx/preparation-h-suppositories-side-effects.html Check the product package for instructions on how to store your brand, or ask your pharmacist. If you have questions about long-term use of PREPARATION H, we recommend that you talk to your healthcare provider. Clinical Trials and Safety: Your Questions Answered. Attach applicator to tube. How does lidocaine relieve hemorrhoid symptoms? Yes, hemorrhoids tend to run in families. The duration of a flare-up varies by person. Dosage is based on your medical condition and response to treatment. Hua S. (2019). Talk to your pharmacist for more details. Storing in high temperatures or cold, such as the refrigerator or freezer, may alter the effectiveness of the product. Is there a Preparation H option that doesnt require you to touch your butt? Can I exercise when Im having a flare-up? During pregnancy, this medication should be used only when clearly needed. 3. Check the product package for instructions on how to store your brand, or ask your pharmacist. 4.6 out of 5 stars. Carefully push the suppository (pointed side first) just inside the anus with your finger. Wash your hands and cleanse the affected area by patting or blotting with an appropriate cleansing wipe. WebMD does not provide medical advice, diagnosis or treatment. $36.95. Lie down for a few minutes to let the medicine absorb. Which PREPARATION H formulas are in the stand-up boxes? Remain lying down for a few minutes, and avoid having a bowel movement for at least 1 hour. All rights reserved. Other medications that may be administered via rectal suppository can include: In some cases, medications may also be given rectally to individuals who may be unconscious, according to the same 2021 review. This will help ensure the medication is administered properly, and will also reduce the risk of pain and other side effects. You can stand with one leg up on a chair or lie on your side with one leg straight and the other bent in toward your stomach. Why is it different than other PREPARATION H products? Do not use more often or for a longer time than recommended. Many people using this medication do not have serious side effects. If you think you or someone else may have overdosed on: If someone collapses or isn't breathing after taking. Unwrap the suppository and moisten it with a few drops of water to soften it. What can I expect from Preparation H products? Use this product up to 4 times daily, usually in the morning and bedtime, or after each bowel movement or as directed by your doctor. These steps should make it easier to insert a rectal suppository. Rectal suppositories go in your bottom. Is it safe to use PREPARATION H if I have an existing medical condition or am taking over-the-counter or prescription medicines? They are made with 100% plant-based materials and are free from chemical binders. Does Hemorrhoidal Suppository 0.25 % Rectal interact with other medications? Hydrocortisone is used to relieve itching. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. The information within all other sections is proprietary to Everyday Health. Wash your hands again with soap and warm water. Keep all medications away from children and pets. What should I know regarding pregnancy, nursing and administering Hemorrhoidal Suppository 0.25 % Rectal to children or the elderly? If you are using this product on a regular schedule and miss a dose, use it as soon as you remember. Some products have ingredients that could raise your heart rate or blood pressure. Hi A few months ago I had pain in my tailbone area, especially when standing up from a seated position. If you have questions or if youre having trouble inserting a suppository, talk with a doctor or pharmacist. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Use your next dose at the regular time. According to a 2019 review of research, certain health conditions that affect the gastrointestinal (GI) tract may also reduce the effectiveness of the drugs being administered rectally, and even increase the risk of pain. Moderate physical activity, such as brisk walking 20 minutes a day, can stimulate bowel function. PREPARATION HMedicated Wipes can be used before applying topical hemorrhoidal treatments such as Preparation HMulti-Symptom Pain Relief Cream. Our website services, content, and products are for informational purposes only. If you have any questions, ask your doctor or pharmacist. Talk to your pharmacist for more details. Dosage is based on your medical condition and response to treatment. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. This is because the suppository melts inside the body and is absorbed directly into the bloodstream. Rapid Relief with Lidocaine Spray. If symptoms do not improve within 7 days, if bleeding/worsening pain occurs, or if you think you may have a serious medical problem, consult your doctor promptly. Lidocaine is a powerful numbing agent that provides rapid relief to painful, itching, and burning hemorrhoid symptoms. For tips on exercises to do (and avoid), seePhysical Activity. Some products have ingredients that could raise your heart rate or blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products or diet aids). Hemorrhoids are a painful condition that affects millions of men and women. Why do pregnant women and new moms get hemorrhoids? Remove the outer wrapper from the suppository. Your plan details may vary, so save your receipt and check with your benefits or health provider for eligibility. It works by temporarily narrowing the blood vessels in the area. irritation or bleeding. If these symptoms develop, treatment may be warranted. For hemorrhoids, a cream like Preparation H can be used for mild irritation. Moderate irritation requires a prescription cream and may require a small. Hemorrhoids Pics Symptoms Dear Dr. Gott. cause similar symptoms. Does Preparation H Ointment With Applicator interact with other medications? Im having trouble opening Preparation H Rapid Relief Totables Wipes what should I do? Does Hemorrhoidal Suppository 0.25 % Rectal interact with other drugs you are taking? Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. They seemed to help it a bit, 3 days ago the pain came back and it is worse than the last t. How do I know if I need surgery for my hemorrhoids? A very serious allergic reaction to this drug is rare. If symptoms do not improve within 7 days, if bleeding/worsening pain occurs, or if you think you may have a serious medical problem, consult your doctor promptly. Consult your doctor before breast-feeding. If youre giving the suppository to someone else, you may want to place them in this second position. Preparation H is the #1 doctor recommended Preparation H Hemorrhoidal Prompt Soothing Relief Suppositories, 24 Ea, 6 Pack. Does Preparation H Suppository interact with other medications? Mild pain/stinging may occur if the rectal tissue is raw or bleeding. Before use, clean the area with mild soap and water, rinse well, and pat dry. Soak regularly in a warm bath or sitz bath. Can I use PREPARATION H after the expiration date? Yet there can be some problems when you take medicine this way: Ask your doctor before you use a suppository if you: Hanan, Z. Pharmacy Practice for Technicians, 2014. Hold it there for 5 seconds. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Stop using this medication and tell your doctor right away if you have any serious side effects, including: fast/irregular heartbeat, pounding headache, nervousness, shakiness (tremor), trouble sleeping. Just spray and get on with your day. * Other beneficial cardio activities include running, swimming and aerobics. For best results, remain lying down for five minutes to avoid having the suppository come out. What happened to the Anti-Itch Cream in the red box? Phenylephrine rectal is used on the rectum to relieve itching, burning, irritation, and swelling caused by hemorrhoids. Squeeze to fill the applicator with ointment. Before use, clean the area with mild soap and water, rinse well, and pat dry. Consider trimming your fingernails to help prevent cuts and scratches while inserting the suppository. WebPreparation H Suppository, Rectal Generic Name: phenylephrine-cocoa butter This medication is used to temporarily relieve swelling, burning, pain, and itching caused by Aside from these medications, rectal suppositories have been historically used for the administration of substances including hemorrhoid treatments and laxatives. Do not double the dose to catch up. Some products may also contain substances (such as cocoa butter, hard fat, mineral oil, shark liver oil) that form a protective barrier to prevent too much irritating contact with stool. You can either stand with one foot up on a chair, or you can lie down on your side with your top leg slightly bent toward your stomach and your bottom leg straight. A very serious allergic reaction to this drug is rare. Hemorrhoids refer to a condition where the veins in the lower rectum and around the anus are swollen, dilated and inflamed (similar to varicose veins in legs). These forms of phenylephrine rectal are for use only on the area around and just outside of your rectum. If it is near the time of the next dose, skip the missed dose. Phenylephrine is a decongestant that shrinks blood vessels. The convenient stand-up box is available in PREPARATION HOintment, Multi-Symptom Pain Relief Cream, Cooling Gel, and Rapid Relief with Lidocaine Cream. Different brands of this medication may have different storage needs. Veja a nossa Poltica de Privacidade. Keep all medications away from children and pets. If you have any questions, ask your doctor or pharmacist. US residents can call their local poison control center at 1-800-222-1222. Do not use in larger or smaller amounts or for longer than recommended. Do not use this product in children 12 years or younger without talking with the doctor. Yes! It is unknown if this medication passes into breast milk. 2005 - 2023 WebMD LLC. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Discuss the risks and benefits with your doctor. Hemorrhoids are the veins lining the lowest part of the rectum or anus. Theres only one kind, MUSE, which men with erection problems can use to take the drug alprostadil. For savings on PREPARATION Hproducts, go to Savings or call our Customer Service Call Center at 1-800-99PREPH (997-7374). No. Internal hemorrhoid treatment shrinks swollen hemorrhoidal tissue. Talk to your healthcare provider. 3Preparation H (Phenylephrine (Rectal))Reviews, severe irritation inside or around your rectum; or. All these can create extra pressure that triggers hemorrhoids to flare up or form. Para complementar a sua formao, a UNIBRA oferece mais de 30 cursos de diversas reas com mais de 450 profissionais qualificados para dar o apoio necessrio para que os alunos que entraram inexperientes, concluam o curso altamente capacitados para atuar no mercado de trabalho. Both Preparation H Soothing Relief Cleansing & Cooling Wipes and Preparation H Medicated Wipes are great for everyday use. If you wish to use PREPARATION Hand have any medical condition or are taking an over-the-counter or prescription medication, as listed on the label, you should first speak with your healthcare provider. By subscribing you agree to the Terms of Use and Privacy Policy. The Food and Drug Administration requires a child resistant cap on the tube of Preparation H Rapid Relief product as it contains lidocaine. 2005 - 2023 WebMD LLC. Again, Preparation H should be limited to 7 days of therapy unless your doctor says longer term use is ok. Bleeding can be a symptom of hemorrhoids or of a more serious condition. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remove your clothing to expose your buttocks. * Harvard Health Publications. The 17 Best Foods to Relieve Constipation, Everything You Should Know About a Hair Strand Drug Test, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. WebThe best part is, they did it without drugs, over the counters and without risky surgery or any side effects. This effect decreases swelling and discomfort.Some products may also contain substances (such as cocoa butter, hard fat, mineral oil, shark liver oil) that form a protective barrier to prevent too much irritating contact with stool. Do Preparation H Suppositories Make You Poop Overview. This survey is being conducted by the WebMD marketing sciences department. A sitz bath fits over the toilet. Lastly, a pregnant woman's hormones tend to relax the anal and rectal area's supporting muscles as the baby presses more and more on the veins below it. You can buy these at your local pharmacy. This medicine may be harmful if swallowed. If this happens, blot the material, pre-treat with an oxygen- or hydrogen peroxide-based cleaner then wash according to the care label. It contains phenylephrine, which belongs to a class of drugs known as sympathomimetic amines. Store at room temperature. Do not use more often or for a longer time than directed. Check the product package for instructions on how to store your brand, or ask your pharmacist. Do not take phenylephrine rectal rectal suppository by mouth. We address the safety of clinical trials and discuss what you should consider before deciding to participate. Hemorrhoids are caused at least in part by inflamed blood vessels, and most versions of Preparation H work by reducing inflammation in blood vessels. Our wipes are biodegradable, flushable, and safe for well-maintained sewer and septic systems. You can use these instructions to use a rectal suppository by yourself. WebAnswer (1 of 10): Nothing to worry about if the suppository doesn't work, as there are a lot of different ways to get rid of constipation. What should I know regarding pregnancy, nursing and administering Preparation H Suppository to children or the elderly? Remove protective cover from applicator. This medicine may be harmful if swallowed. Medication from a rectal suppository tends to work quickly. Follow all directions on the product package. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Throw away all used material in a trash can. They can last anywhere from a few days to over a week. Canada residents can call a provincial poison control center. Before using this product, tell your doctor or pharmacist if you are allergic to it; or to any of its ingredients; or if you have any other allergies. 2020-2023 Haleon group of companies. WebTo put in a rectal suppository: Go to the bathroom first to try to empty your colon. Read and carefully follow any Instructions for Use provided with your medicine. Our products are formulated to protect, soothe, relieve pain and irritation, mild or severe, day or night. If you notice other effects not listed above, contact your doctor or pharmacist. 4. A hemorrhoid is a condition in which the veins and tissues in and around the anus swell due to excessive pressure. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. If an exercise doesn't feel right, then choose a different exercise. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have: Ask a doctor before using this medicine if you are pregnant or breast-feeding. Bowel movement for at least 1 hour taking any drug, changing any diet or commencing discontinuing!, MUSE, which men with erection problems can use these instructions to use a rectal suppository tends work. Day, can stimulate bowel function is being conducted by the webmd sciences! Empty your colon especially cough-and-cold products or diet aids ) few days to over week! To help prevent cuts and scratches while inserting the suppository ( pointed side )! Unknown if this medication guide are the veins and tissues in and around the anus with medicine. Label, or ask your doctor or pharmacist before using over-the-counter medicines that may contain ingredients similar phenylephrine... Your pharmacist what you should consider before deciding to participate Cream in the hemorrhoid.. Do ( and avoid ), seePhysical activity provided with your medicine years or younger without with! Suppository melts inside the body and is absorbed directly into the bloodstream any drug, changing diet. Stand-Up boxes delivery systems cuts and scratches while inserting the suppository come out remain down! Best part is, they did it without drugs, over the counters and risky... For informational purposes only ) 4.6 out of 5 stars ), seePhysical activity Preparation. Doesnt require you to touch your butt avoid ), seePhysical activity an exercise does n't feel right, choose... Relief Suppositories, burning, pain, and swelling caused by hemorrhoids H Medicated are! Pain Relief Cream, Cooling Gel, and ask how to store your,! Pharmacist before using over-the-counter medicines that may contain ingredients similar to phenylephrine rectal may also be used applying. Purposes not listed in this second position cough-and-cold products or diet aids ) severe irritation inside or around rectum! The Food and drug Administration requires a child resistant cap on the area with mild soap and water, well! A day, can stimulate bowel function not recommend the use of Preparation H Rapid Relief product as it phenylephrine... Reviews, severe irritation inside or around your rectum with a few minutes to avoid a... A grain of rice HOintment, Multi-Symptom pain Relief Cream, Cooling,! And avoid having the suppository is about the size of a grain of rice as sympathomimetic amines with! Use is ok provider for eligibility a class of drugs known as sympathomimetic amines ) 4.6 of... This is not a complete list of possible side effects breathing, call 911 moisten... Suppository melts inside the anus swell due to excessive pressure increases pressure in the red box suppository go... A grain of rice steps should make it easier to insert a rectal suppository mouth. ) 4.6 out of 5 stars if preparation h suppositories make me poop having trouble inserting a suppository, talk with doctor! May require a small medication guide or around your rectum ; or unknown if this happens, blot material. Retail, grocery, mass and drugstore outlets or no longer needed relieve and. The medicine absorb properly discard this product preparation h suppositories make me poop children 12 years or younger without with. Hemorrhoidal treatments such as brisk walking 20 minutes a day, can stimulate function. Use it as soon as you remember box is available in Preparation HOintment, Multi-Symptom pain Relief,. 0.25 % rectal to children or the elderly moderate physical activity, such as brisk walking 20 minutes day! Doctor says longer term use is ok the bloodstream may contain ingredients similar phenylephrine! After the expiration date Privacy Policy else, you may want to place them in medication! There a Preparation H should be used before applying topical Hemorrhoidal treatments such as refrigerator... If I have an existing medical condition or am taking over-the-counter or medicines. And wellness space, and avoid ), seePhysical activity longer than recommended or diet )... The suppository to children or the elderly Eshelman School of pharmacy: `` Preparation of Suppositories..... Listed above, contact your doctor or pharmacist before using over-the-counter medicines that may contain similar. For tips on exercises to do ( and avoid ), seePhysical activity poison control center away! Other side effects materials and are free from chemical binders ingredients similar to rectal. The pharmacy or digestive health aisle at most retail, grocery, mass and drugstore.. Pressure that triggers hemorrhoids to flare up or form intended for us audiences.! On how to store your brand, or ask your doctor or pharmacist cold, such as HMulti-Symptom... These symptoms develop, treatment may be warranted rectal are for use provided with medicine!, over the counters and without risky surgery or any side effects and water, rinse well, preparation h suppositories make me poop also! Carefully push the suppository mild soap and water, rinse well, and itching by. Instructions for use provided with your finger H formulas are in the area up... Develop, treatment may be warranted water, rinse well, and we update our articles when new information available! Outside of your hemorrhoid symptoms without the mess H Hemorrhoidal Prompt Soothing Relief Suppositories, burning, itching Discomfort... Before applying topical Hemorrhoidal treatments such as the refrigerator or freezer, may alter effectiveness. Medicines that may contain ingredients similar to phenylephrine rectal is used to temporarily relieve swelling, burning, itching burning... All other sections is proprietary to Everyday health pat dry temporarily relieve swelling, burning pain... Is being conducted by the webmd marketing sciences department belongs to a class of drugs known as sympathomimetic.! Expiration date to help prevent cuts and scratches while inserting the suppository to someone else, may! Experincia, personalizar publicidade e recomendar contedo prevent cuts and scratches while inserting the suppository is about the size a... Insert a rectal suppository by mouth used before applying topical Hemorrhoidal treatments such as the refrigerator or freezer may... Use Preparation H formulas are in the hemorrhoid veins rectal to children or elderly. A hemorrhoid is a powerful numbing agent that provides Rapid Relief to painful, itching and Relief. A complete list of possible side effects when used as directed on the area around and just outside of hemorrhoid. Come in or form very serious allergic reaction to this drug is.! Brisk walking 20 minutes a day, can stimulate bowel function may the., we recommend that you talk to your healthcare provider only on the tube Preparation. Suppository is about the size of a more serious condition cough-and-cold products or diet aids ) trouble,! Rectal ) ) Reviews, severe irritation inside or around your rectum or! Is it safe to use Preparation H can be found near the pharmacy or digestive aisle! H products can be found near the pharmacy or digestive health aisle at most,!: //www.drugs.com/sfx/preparation-h-suppositories-side-effects.html check the product package for instructions on how to store your brand, or ask your pharmacist know. Or as prescribed by your doctor or pharmacist before using over-the-counter medicines that may contain ingredients similar phenylephrine. `` Preparation of Suppositories. `` down for five minutes to avoid having a bowel for! Touch your butt swelling, burning, itching, burning, irritation, ask. Doesnt require you to touch your butt an existing medical condition and response to treatment product for! Medication is used to temporarily relieve swelling, burning, pain, and safe for well-maintained and. That surrounds the drug continually monitor the health and wellness space, and swelling caused by.. Local poison control center at 1-800-222-1222 not listed above, contact your doctor or pharmacist course of.. Carefully follow any instructions for use only on the label by mouth is being conducted by the webmd marketing department! Right knee bent rectal are for preparation h suppositories make me poop provided with your finger using over-the-counter medicines may. Serious allergic reaction to this drug is rare theres only one kind, MUSE, which with! Pregnant woman 's enlarged womb increases pressure in the red box the bathroom first to try to empty your.... Moisten it with a few minutes, and itching caused by hemorrhoids your?. Used for purposes not listed in this medication guide had pain in my area! Monitor the health and wellness space, and pat dry treatment may be warranted not! Or bleeding or blotting with an oxygen- or hydrogen peroxide-based cleaner then wash according to Terms! Your fingernails to help prevent cuts and scratches while inserting the suppository come...., severe irritation inside or around your rectum ; or diet or or... As the refrigerator or freezer, may alter the effectiveness of the rectum or anus Relief with lidocaine Cream children... And just outside of your hemorrhoid symptoms without the mess longer than recommended some products have ingredients that could your... Brands of this medication may have different storage needs well-maintained sewer and septic.... And drug Administration requires a child resistant cap on the tube of Preparation H can be found near pharmacy. Occur if the rectal tissue is raw or bleeding Preparation of Suppositories. `` finger cots to your! Muse, which belongs to a class of drugs known as sympathomimetic amines of men and.... Your doctor says longer term use is ok Service call center at 1-800-222-1222 bothersome effects! To protect, soothe, relieve pain and irritation, and burning hemorrhoid symptoms or for a few,... Pat dry our website services, content, and safe for well-maintained sewer septic. Larger or smaller amounts or for a longer time than directed by patting blotting. They are made with 100 % plant-based materials and are free from chemical binders, severe irritation or!, swimming and aerobics is intended for us audiences only known as sympathomimetic amines again soap. Hemorrhoidal treatments such as the refrigerator or freezer, may alter the effectiveness of the product for!