If you accidentally get the powder or oral suspension on the skin, wash the area well with soap and water. Theyll likely also check your red blood cell counts regularly during your treatment. To better understand your condition, they may ask about other symptoms youre experiencing. If you think youve taken too much of this drug, call your doctor. Examples of other drugs that may be used to help prevent organ rejection after a transplant include: Some of these medications may be taken along with CellCept. In this situation, your doctor may give you the CellCept infusion for up to 14 days. For more information, see the Boxed warnings section under CellCept side effects.. This is because exposure to the CellCept powder or liquid may cause congenital anomalies (also known as birth defects) or pregnancy loss. CellCept was compared with azathioprine (Azasan, Imuran) in clinical studies of adults who had a liver transplant. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. CellCept is an immunosuppressant (a drug that weakens your immune system). Studies in rats that were given CellCept showed the drug was present in milk. To decrease your risk for skin cancer while using CellCept, you should limit your time spent in the sun. Possibly. To learn more, call 800-617-8191, visit the registry website, or talk with your doctor. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. Some medicines may affect the way CellCept works, and CellCept may affect how some medicines work. Its also available as an intravenous (IV) infusion* (an injection into a vein over a period of time) thats given by your doctor. Brain- People report more pain, headache, and confusion on this drug. Also tell them about any vitamins, herbs, and supplements you use. It isnt safe to take CellCept during pregnancy. If contact occurs, rinse thoroughly with water. What drugs and food should I avoid while taking Cellcept (Mycophenolate Mofetil (Oral/Injection))? Specifically, CellCept is a type of immunosuppressant called an antirejection drug. Tell them about all prescription, over-the-counter, and other drugs you take. It works by inhibiting the inosine monophosphate dehydrogenase enzyme, preventing B-cell and T-cell lymphocytes from multiplying. A generic drug is an exact copy of the active drug in a brand-name medication. If you need financial support to pay for CellCept, or if you need help understanding your insurance coverage, help is available. ), The typical dosage of CellCept for preventing rejection of a liver transplant is 1,500 mg taken twice per day. This can raise your risk for side effects from drugs that are cleared through kidney tubules. Check with your doctor right away if you have bloody urine, decreased frequency or amount of urine, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, vomiting, or weight gain. No, CellCept tablets or capsules cant be crushed, split, or chewed. CellCept may also be used off-label for other conditions, including: If youd like more information on the use of CellCept in treating these conditions, talk with your doctor. The actual price youll pay for any of these drugs depends on the form you use, your treatment plan, your insurance plan, your location, and if applicable, the pharmacy you use. And animal studies dont always indicate what may happen in humans. Weight gain while taking prednisone is typically due . For instance, some interactions can interfere with how well a drug works. Call your doctor if you are not sure what to do. If youre concerned about hair loss while using CellCept, talk with your doctor. Hair loss isnt a side effect of CellCept thats been reported in clinical studies. Taking CellCept can increase your risk for serious infections. Possibly. * The CellCept IV infusion is used for people who arent able to swallow CellCept capsules, tablets, or liquid. Both CellCept and Prograf are FDA-approved to help prevent organ rejection* after a heart, kidney, or liver transplant. Its available in the following forms and strengths: The first oral dose of CellCept should be given as soon as possible after a kidney, heart, or liver transplant. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. A kitchen timer can work, too. Is the ketogenic diet right for autoimmune conditions? No, CellCept isnt a chemotherapy drug. CellCept contains the active drug mycophenolate mofetil. Then take your next dose at its usual time. If you drink alcohol and have questions about drinking alcohol while using CellCept or after having an organ transplant, talk with your doctor. Taking CellCept with phosphate binders can lower your blood levels of CellCept, making CellCept less effective. It can take up to 12 weeks for CellCept to start working to help prevent organ rejection. You should not donate blood while taking CellCept and for at least 6 weeks after stopping CellCept. These tests will make sure the donated organ matches your body as closely as possible. You should always consult your doctor or another healthcare professional before taking any medication. Take Mycophenolate either 1 hour before or 2 hours after eating. Tell your doctor about any side effect that bothers you or that does not go away. Taking CellCept may increase your risk for certain types of cancers, including lymphoma (a type of cancer that starts in your white blood cells) and skin cancer. Examples of immunosuppressants used with CellCept include corticosteroids and cyclosporine (Neoral, Sandimmune). The recommended oral dosages in children are as follows: If you miss a dose of CellCept, take your missed dose as soon as you remember. Before approving coverage for CellCept, your insurance company may require you to get prior authorization. Learn more here. Examples of antacids that contain magnesium hydroxide or aluminum hydroxide include: To lower the risk of this interaction, its recommended that you take antacids at least 2 hours after your dose of CellCept. The dosage for CellCept varies depending on its use. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. A boxed warning is the most serious warning from the FDA. Youll also need to check your insurance plan, as it may only cover one or the other. This can raise your risk for side effects. Some people may experience a rash while taking CellCept. Promptly consult your doctor or pharmacist. Some medications are cleared from the body through kidney tubules (small tubes in the kidney that filter your blood). As a way of protecting your body, your immune system will try to get rid of it. 50 are major, 229 are moderate, and 29 are minor. CellCept can interact with antacids (medications used to relieve heartburn or indigestion) that contain magnesium hydroxide or aluminum hydroxide. have Lesch-Nyhan syndrome, Kelley-Seegmiller syndrome, or another rare inherited deficiency hypoxanthine-guanine phosphoribosyl-transferase (HGPRT). If you would like to notify the FDA about a side effect youve had with CellCept, you can do so through MedWatch. You should not donate sperm while taking CellCept and for 90 days after stopping CellCept. However, clinical guidelines recommend using CellCept for lupus in adults who also have signs of kidney disease. Scientists are now investigating whether it may benefit, Blood circulates throughout the body, transporting substances essential to life. Your reason for needing an organ transplant can also affect the amount of alcohol thats safe for you to drink. (Phosphate is a chemical that naturally occurs in the body.). You should avoid getting live vaccines while taking CellCept. This drug has boxed warnings. Avoid using tanning beds or sunlamps. There arent any herbs or supplements that have been specifically reported to interact with CellCept. These lists contain examples of serious side effects that can occur with CellCept, with Prograf, or with both drugs (when taken individually). Your . Its also supported by additional data from use in children. Off-label drug use is when a drug thats FDA-approved for one or more uses is prescribed for a different one thats not approved. * CellCept and Myfortic have boxed warnings for these side effects. Drink ice-cold or clear drinks (for example, unsweetened tea or water) Avoid foods that are sweet, greasy, or fried. Serious infections can happen with CellCept and can lead to hospitalizations and death. CellCept is available as a generic drug called mycophenolate mofetil. Before you start using CellCept, be sure to tell your doctor if you take any PPIs. There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Generics tend to cost less than brand-name drugs. They can discuss with you the risks and benefits of continuing your CellCept treatment. Talk with your doctor about whether youre up to date on all recommended vaccines before starting CellCept. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. However, swelling in the ankles, feet, or legs can occur with this drug. stop taking CellCept. CellCept is FDA-approved to help prevent organ rejection in children ages 3 months and older. Avoid combinations; the risk of the interaction outweighs the benefit. CellCept is indicated for use in combination with other immunosuppressants to help prevent organ rejection after a heart, liver, or kidney transplant. Granulocyte colony stimulating factor (G-CSF) is a type of drug that doctors prescribe to manage neutropenia. . (Having a stable transplant means you arent experiencing any symptoms of organ rejection. Do not cut, crush, or chew the medicine. Congenital anomalies that were reported include facial abnormalities such as cleft lip and palate, and heart defects. They make your body less likely to reject a transplanted organ. For more information about taking CellCept during pregnancy, see the CellCept and pregnancy section above. If your doctor has prescribed CellCept and youre interested in using mycophenolate mofetil instead, talk with your doctor. It alerts doctors and patients about drug effects that may be dangerous. Swallow the tablets whole. If you have questions about using CellCept with antacids, talk with your doctor. For information on the effectiveness of CellCept, see the CellCept uses section below. Can diet help improve depression symptoms? Avoid soft mold-ripened and blue-veined cheeses such as Brie, Camembert, Roquefort, Stilton, Gorgonzola and Bleu or other soft, unpasteurized cheeses. Steer clear of inflammatory foods such as grains and legumes, nightshades, gluten, and dairy. The most common symptom of anemia is fatigue. This is because drinking alcohol can lead to health problems that cause extra strain on your transplanted organ, such as hypertension (high blood pressure). CellCept is available in a generic form called mycophenolate mofetil. However, data from pregnancy registries shows that 45% to 49% of people who took CellCept while pregnant had a pregnancy loss in the first 3 months of their pregnancy. To give an example, for a child whose body surface area is 1.25 m2, the typical dose is 750 mg taken twice per day. All three treatments were given with corticosteroids and cyclosporine. This extra fluid in your body can make it seem like youve gained weight. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Storage requirements for CellCept vary with each formulation: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. To help lessen this immune system reaction, your doctor will order several tests for you and the organ donor before your transplant. Please see fullPrescribing Information,including Boxed WARNINGS and Medication Guide, for additional Important Safety Information. Before using CellCept, be sure to tell your doctor about any other medications youre taking. It isnt known how many people who used a placebo may have had depression. The generic is considered to be as safe and effective as the original drug. This works in cancer treatment because cancer cells grow more quickly than normal healthy cells. How does blood work, and what problems can occur? You should wash the affected area of skin right away, even if you arent able to get pregnant. Also, right after your healthcare professional has used a syringe, needle, or autoinjector, theyll dispose of it in an FDA-approved sharps disposal container. Researchers wanted to see how effective each treatment was at preventing treatment failure. CellCept may influence your ability to drive and use machines (See, blood problems including low white and red blood cell counts, swelling of the lower legs, ankles and feet, changes in laboratory blood levels, including high levels of blood sugar (hyperglycemia), stomach problems including diarrhea, constipation, nausea and vomiting, nervous system problems such as headache, dizziness and tremor. Generally speaking, the higher the dose and the longer the treatment, the greater the changes. See. If your skin comes in contact with the powder from CellCept capsules or the liquid that you swallow, wash the affected area of skin right away. Here we look at how these drugs are alike and different. In clinical studies: In these studies, it isnt known how many people may have died from a serious infection while using other treatments. Stem cell therapy may help reduce inflammation and build up healthy cells in the body. Its important to note that the oral dosage forms are not interchangeable with mycophenolic acid delayed-release tablets. This form of Prograf is also typically taken twice per day. (Skin spots may be discolored, scaly, or crusty.). CellCept and Myfortic are both brand-name drugs. CellCept is metabolized (broken down) in the body by a process called glucuronidation. Your pharmacist will mix the medicine before you pick it up from a pharmacy. Prograf is available as a generic drug called tacrolimus. (For more information, see the Taking CellCept with food section below.). These lists dont include all possible side effects. . Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. This happens because the immune system doesnt recognize the new organ as part of your body. There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). However, its important that you keep taking CellCept even if you dont notice that its working. Prograf is also FDA-approved to help prevent organ rejection after a lung transplant in adults and children.. If you accidentally get the powder or oral suspension in your eyes or other mucous membranes, flush with plain water. Both drugs were given with corticosteroids and cyclosporine (Neoral, Sandimmune). Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. 6 disease interactions, and 1 alcohol/food interaction. * This is a partial list of mild side effects from CellCept. You can also refrigerate the liquid at temperatures of 36F to 46F (2C to 8C). Both of these forms are typically taken twice per day. In clinical studies of adults, CellCept was compared with azathioprine and a placebo (a treatment with no active drug). The generic is considered to be as safe and effective as the original drug. Examples of antibiotics that may need to be avoided while taking CellCept include: Be sure to tell your doctor if youre taking any antibiotics while using CellCept. This can include setting an alarm on your phone or downloading a reminder app. have any digestive problems, such as ulcers. * For this purpose, CellCept is approved for use in children ages 3 months and older. Its FDA-approved to help prevent organ rejection* after a heart, kidney, or liver transplant. It is indicated for use in adults and children ages 3 months and older. Phosphate binders are often used in people who have kidney problems and are receiving dialysis. Birth control pills may not work as well while you take CellCept, and you could become pregnant. Consult your healthcare professional (e.g.,. As a way of protecting your body, your immune system will try to get rid of it. (Organ rejection occurs when the immune system attacks a transplanted organ.). We comply with the HONcode standard for trustworthy health information. CellCept can affect your ability to drive or operate machines. It works by preventing immune cells from multiplying. These drugs make your body less likely to reject a transplanted organ. If taken with CellCept, these antacids can lower the amount of CellCept in your body. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is possible. The Prograf infusion is given as a continuous infusion, which can last from a few hours to days. Keep a list of them to show to your doctor or nurse and pharmacist when you get a new medicine. Most people who have had organ transplants take CellCept both right after transplantation and for the long term. If you take too much CellCept, call your doctor or the poison control center right away. Phosphate binders are a group of drugs that are used to remove high levels of phosphate from your body. Serious inflammatory response, which can develop weeks to months after starting treatment or after a dosage increase. However, live vaccines could cause infections in people whose immune systems are weakened, including those taking immunosuppressants such as CellCept. Treating scleroderma isnt an FDA-approved use for CellCept. Myfortic contains the active ingredient mycophenolic acid. Your doctor or pharmacist will advise you about the correct dose. Because CellCept weakens your immune system, getting a live vaccine while taking CellCept can make the live vaccine less effective. However, chemotherapy drugs cant tell the difference between healthy cells and cancer cells. If you have questions about getting anemia while using CellCept, talk with your doctor. Organ rejection can happen within days or weeks of the transplant. For more information on these side effects, see Side effect details below. Symptoms of lymphoma can be similar to symptoms of the common cold, such as fever and a runny or stuffy nose. You should have one pregnancy test right before starting CellCept and another one 8 to 10 days later. Minimally clinically significant. Other interactions can increase side effects or make them more severe. CellCept can cause mild or serious side effects. Do not use more CellCept than your doctor recommends. If the medicine is broken or is not intact, do not get the powder on your skin or eyes. This lowers your immune systems ability to attack the newly transplanted organ. These lists dont include all possible side effects that may occur with each drug. Symptoms of infection can vary depending on whether its bacterial, viral, or fungal. Minor multivitamins with minerals mycophenolate mofetil Minor Drug Interaction Information for this minor interaction is available on the professional version. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. (Scleroderma is a condition that affects the bodys skin and tissues.) However, be sure to take the dosage your doctor prescribes for you. CellCept decreases blood levels of the hormones in birth control pills that you take by mouth. CellCept is meant to be used as a long-term treatment. Different interactions can cause different effects. Here we look at how CellCept and Myfortic are alike and different. MS: Can the Mediterranean diet help preserve cognitive health? Organ rejection occurs when your immune system attacks a transplanted organ. (For more information on the drugs side effects, see CellCept side effects above.). Whole grains contain more fiber, protein, and micronutrients than refined grains. Highly clinically significant. A boxed warning is the most serious warning from the FDA. * PPIs are medications used to treat conditions such as heartburn or gastroesophageal reflux disease. The generic is considered to be as safe and effective as the original drug. you are allergic to any other medicines, foods, dyes or preservatives. The capsule forms of both drugs are typically taken twice per day. Before you start CellCept, tell your doctor about any medications youre taking. The risk of pregnancy loss is highest during the first 3 months of pregnancy. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. Do not take CellCept if you are allergic to mycophenolate mofetil or any of the ingredients in CellCept. CellCept is contraindicated in people with a known allergy to any of its ingredients. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. However, this drug hasnt been studied in breastfeeding people. Eat smaller meals. BK virus can affect how your kidney works and cause your transplanted kidney to fail, hepatitis B and C viruses. For information on how the drug performed in clinical studies, see CellCepts prescribing information. This site is intended for U.S. residents only. They can recommend ways to treat this side effect. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Myfortic is available as a generic drug called mycophenolate sodium. For more information on the possible side effects of CellCept, talk with your doctor or pharmacist. Avoid combinations; the risk of the interaction outweighs the benefit. oral suspension containing 200 mg per milliliter (mL) of suspension, intravenous infusion containing 500 mg per vial of solution. Each infusion is given by your doctor over a period of about 2 hours. This drug comes with several precautions. CellCept is an antirejection drug that works by preventing immune cells from multiplying. Tell your doctor if you have: Increased risk of getting serious infections. In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug). Myfortic was found to be as effective as CellCept at preventing organ rejection. Lymphoma may also cause swollen lymph nodes that are painful to touch. by visiting the Risk Evaluation and Mitigation Strategy (REMS) website at, unexplained fever, prolonged tiredness, weight loss or lymph node swelling, a brown or black skin lesion with uneven borders, or one part of the lesion does not look like the other, shingles, other herpes infections, and cytomegalovirus (CMV). They can give you tips on how to deal with any side effects that may be bothersome. Taking CellCept with drugs that are cleared from the body in this way can increase the levels of these drugs in your body. If youre taking cholestyramine, be sure to tell your doctor before using CellCept. The IV infusion* is given by your doctor over a period of about 2 hours, twice per day. You may need to avoid crowds and wash your hands often. There are 308 drug interactions with CellCept (mycophenolate mofetil). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. You should understand how the drug affects you before driving. For more information, see the Boxed warnings section under CellCept side effects.. Chemotherapy drugs work by destroying all cells that are growing quickly. Limit the amount of time you spend in sunlight. This article provides several useful tips on medication disposal. People taking CellCept should not receive live vaccines. The results showed that: It isnt known how many people may have had a rash after using a placebo or after using CellCept for other types of transplants. Before starting treatment, talk with your doctor about your risk for cancer while using CellCept. The CellCept dosage your doctor prescribes will depend on several factors. There arent any known interactions between CellCept and alcohol. Your healthcare professional will store the powder and intravenous solution. They can be prescribed to adults and children.. * The IV infusion is used for people who arent able to swallow CellCept capsules, tablets, or liquid. Prograf can be taken with or without food. (Cyclosporine is also an antirejection drug.). Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, What to know about granulocyte colony stimulating factor (G-CSF), All about hematopoietic stem cell transplantation, Stem cell therapy for rheumatoid arthritis. 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